Really, I find that you really don't get enough juice from the squeeze, so to speak, when you start measuring into the 1/100th scale. I mean, depending on what powder you're measuring, you'd have to cut individual grains to even be able to pursue that kind of accuracy... there are lots of people that go by volume, too - or even titrate to effect. I mean, a nice light, fluffy, fine grained powder like you'd get from evaporated ketamine or a really pure cocaine might make it worth it. Certainly if you're dealing with fentanyl you need a really fine measurement scale that will do 1/1000ths, but, let's be honest, if you're loading up on that stuff before you go out doing hood rat shit and booging down like a goddamn clown in true goon fashion, you're experienced enough to just eyeball it all... plus you've probably got enough tolerance to work as a buffer if you dose a little too high. Just my two cents, though.

If we're talking gunpowder, then all this still rings true, but I'd really just fill the case up and pound that bullet in with a good rubber mallet or a quality floppy black silicone dildo until you hear the powder make a sound similar to your mouth when you're gobbling down some potato chips (assuming that you actually chew them). Again, just titrate to effect.

Hope this helps!