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lanre 1 point ago +1 / -0

This is the same setup I have, same concept of a rifle to do a bit of everything. Overall I'm pretty impressed. Downsides I've noticed so far (mine is a cheap build):

1.) Lower ammo/magazine capacity (duh) 2.) Increased recoil. A 5.56 AR is like shooting a 22LR and allows for fast follow-up shots. A 6.5 grendel with a short barrel isn't bad, but it's a little worse. Also, a pistol brace isn't as good as a stock, but unfortunately you have to deal with that or an SBR permission slip.
3.) I had some feeding issues with my elander magazines. I'd probably use the smaller capacity ASC magazines if I was in a serious fight since I've had no issues with their reliability.

Upsides, there's a lot.