Asking because local BellasProAss actually has a Savage 110 Tactical Southpaw in 6.5 Meme. And guns in the handedness of Gun Judas are fucking hard to find even in the best of times. But is Mememoore just a fad that is already passing with the PRC's being the new hotness? I know it has seen limited adoption by the military, and my grandpappy said buy shit the military uses, but by army guys who have personal ammo budgets higher than the entire yearly budget of my local sheriff's department. And they can change on a whim should "the mission dictate".
Normally I'd go with .308 because I already stock it for the Cold War Rifle collection, or at least Full NATO. I've avoided Mememoore because if I had followed every trend I'd have a .260 Remington, 6.5 Grendel, 6.8SPC, all of which was to be the next big thing then faded.
I could ask long range shooters, but they're kinda assholes plus sniff the manufactures and guntubers/bloggers farts. Figure autists would be the better perspective.
The thing that would steer me to the 308 would be barrel life. It's something like 2-3x what you get from the 6.5.
With that said, you probably won't have a problem finding ammo in the near future (any more than any other ammo anyway). You certainly won't have an issue finding brass and bullets to keep loading for it. Even a 260 Rem can reasonably be fed.
Here's the thing - lots of people talk about barrel life but the number of people who actually shoot enough to burn out a barrel is very low. I burnt out one 6.5 Creedmoor barrel, after shooting 3,500 rounds of ammo through it. Even reloading that shit at 40cpr that's $1,400 of ammo, and if you shoot factory ammo it's going to be $3,000+ to shoot that much and your barrel might even last a bit longer than mine did since I was using pissin' hot loads (147gr bullets at 2900fps, the same as the factory 6.5 PRC loads).
A nice new Criterion barrel for a Savage rifle will run you $370. The rifle itself cost like $500, and you're worried about the barrel lasting longer than thousands of rounds and dollars worth of ammo down the tube? If you can spend $1,500+ on the ammo required to burn out a barrel, you can spend the $370 to re-barrel that shit afterwards.